Modelová Otázka ID 2940 - 
Vitamín B12 je produkován některými druhy bakterií – např. E. coli, která kolonizuje také lidská střeva. Je produkce B12 pomocí E. coli ve střevech dostatečná na pokrytí spotřeby vitamínu daným člověkem?
Správná odpověď je: D
Vitamín B12 vytvořený pomocí bakterie Escherichia coli ve střevech je bohužel nevyužitelný, protože nedokáže vytvořit komplex s vnitřním faktorem (IF, z anglického intrinsic factor), který se produkuje v žaludku. Pro vstřebání vitamínu B12 je tedy nutné tento vitamín přijímat v potravě a zároveň musí být zachována schopnost žaludku tvořit vnitřní faktor. Při nesplnění kterékoliv z podmínek v předchozí větě vzniká hypovitaminóza B12, která se projevuje jako perniciózní anémie.
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